Scientific Researchers
Learn how to request tissue from the NeuroBioBank or browse our inventory of available samples.
Potential Donors
Learn about the crucial need for brain donation and how your gift can advance human knowledge.
The NIH NeuroBioBank is pleased to announce that genome-wide genotyping and whole genome sequence (WGS) data from 9667 subjects from the NIH NeuroBioBank inventory are now available to the biomedical research community. Please find the publicly available web page for this study in the NIMH Data Archive here. To access, search and analyze this dataset, apply for access here. Once approved, you will be able to access the data in collection #3917. There are helpful tutorials about accessing data here. If the tutorials don't answer the questions you have, you should contact NDAHelp@mail.nih.gov.
Since 2013, the NIH NeuroBioBank has catalyzed scientific discovery through the centralization of resources aimed at the collection and distribution of human post-mortem brain tissue.
Our networked brain and tissue repositories distribute thousands of samples per year to the research community studying neurological, developmental, and psychiatric disorders.
Learn more about the NIH NeuroBioBankLearn how to request tissue from the NeuroBioBank or browse our inventory of available samples.
Learn about the crucial need for brain donation and how your gift can advance human knowledge.
Tuberous sclerosis complex is associated with a novel human tauopathy.
Tuberous sclerosis complex (TSC) is a neurogenetic disorder leading to epilepsy, developmental delay, and neurobehavioral dysfunction. The syndrome is caused by pathogenic variants in TSC1 (coding for hamartin) or TSC2 (coding for tuberin). Recently…
View the abstractAge-related Huntington's disease progression modeled in directly reprogrammed patient-derived striatal neurons highlights impaired autophagy.
Huntington's disease (HD) is an inherited neurodegenerative disorder with adult-onset clinical symptoms, but the mechanism by which aging drives the onset of neurodegeneration in patients with HD remains unclear. In this study we examined striatal m…
View the abstractSARS-CoV-2 invades cognitive centers of the brain and induces Alzheimer's-like neuropathology.
The neurotropism of SARS-CoV-2 and the phenotypes of infected neurons are still in debate. Long COVID manifests with "brain diseases" and the cause of these brain dysfunction is mysterious. Here, we analyze 34 age- and underlying disease-matched COV…
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