Scientific Researchers
Learn how to request tissue from the NeuroBioBank or browse our inventory of available samples.
Potential Donors
Learn about the crucial need for brain donation and how your gift can advance human knowledge.
The NIH NeuroBioBank is pleased to announce that genome-wide genotyping and whole genome sequence (WGS) data from 9667 subjects from the NIH NeuroBioBank inventory are now available to the biomedical research community. Please find the publicly available web page for this study in the NIMH Data Archive here. To access, search and analyze this dataset, apply for access here. Once approved, you will be able to access the data in collection #3917. There are helpful tutorials about accessing data here. If the tutorials don't answer the questions you have, you should contact NDAHelp@mail.nih.gov.
Since 2013, the NIH NeuroBioBank has catalyzed scientific discovery through the centralization of resources aimed at the collection and distribution of human post-mortem brain tissue.
Our networked brain and tissue repositories distribute thousands of samples per year to the research community studying neurological, developmental, and psychiatric disorders.
Learn more about the NIH NeuroBioBankLearn how to request tissue from the NeuroBioBank or browse our inventory of available samples.
Learn about the crucial need for brain donation and how your gift can advance human knowledge.
Somatic mutations in single human cardiomyocytes reveal age-associated DNA damage and widespread oxidative genotoxicity.
The accumulation of somatic DNA mutations over time is a hallmark of aging in many dividing and nondividing cells but has not been studied in postmitotic human cardiomyocytes. Using single-cell whole-genome sequencing, we identified and characterize…
View the abstractCorticosteroid sensitization drives opioid addiction.
The global crisis of opioid overdose fatalities has led to an urgent search to discover the neurobiological mechanisms of opioid use disorder (OUD). A driving force for OUD is the dysphoric and emotionally painful state (hyperkatifeia) that is produ…
View the abstractChromatin domain alterations linked to 3D genome organization in a large cohort of schizophrenia and bipolar disorder brains.
Chromosomal organization, scaling from the 147-base pair (bp) nucleosome to megabase-ranging domains encompassing multiple transcriptional units, including heritability loci for psychiatric traits, remains largely unexplored in the human brain. In t…
View the abstract